Quartz Crystal Microbalance with Dissipation (QCM-D)

Providing answers about mass and structural changes at the nanoscale level with nanogram precision for a wide variety of samples and measurement conditions.

Quantitative Surface & Interface Contamination

Qualitative analysis such as visual inspection of a surface lacks quantitative data. For example, understanding how cleaning agents are performing, from removal rates to total mass removal, is vital to the development of products from CMP Slurries to surfactant in dish detergent. Quartz crystal microbalance delivers quantitative data on how surface and solutions interact at molecular levels, bringing quantitative data to some outdated qualitative testing procedures.

Additional Capabilities

Standard flow module:

Standard module for liquid or gaseous samples.

PTFE module:

Replaces the titanium flow path of standard flow module with PTF for flow or stagnant measurements where the reagents or molecules are sensitive to interactions with titanium.

Ideal for research on:

• Nanoparticle interactions
• Protein interactions
• Surfactant and detergent interactions
• Biomaterial screening
• Hydrolysis
• Asphaltene adsorption

Open module:

For low volume samples without flow, volumes down to ~50 μL.

Ideal for research on:

• Pharmacology
• Mammalian cells
• Self-assembly
• UV curing properties

Humidity module:

To study film interactions such as swelling in contact with different vapors and relative humidity.

Ideal for research on:

• Film and coating hydration
• Polymer swelling
• Food science
• Protein hydration
• Paper and print
• Cellulose

Application Examples

• Protein interaction with container/packaging
• Biomolecule interactions with surfaces
• Flavor and fragrance intensity evaluation
• Detergency effectiveness and surface cleanliness
• Cellular interactions in solution and surfaces
• Quantitative polymer cross-linking
• Biomolecular binding kinetics
• Chromatographic detection
• Viscoelastic modeling