Quartz Crystal Microbalance with Dissipation

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

QUARTZ CRYSTAL MICROBALANCE WITH DISSIPATION (QCM-D)
Quartz Crystal Microbalance with Dissipation
QUANTIATIVE SURFACE & INTERFACE CONTAMINATION

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

QUANTITATIVE | REAL-TIME | CHEMICAL & SURFACE INTERACTIONS

Quartz Crystal Microbalance with Dissipation
QUANTIFY VISCOELASTICITY

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

QUANTITATIVE | REAL-TIME | CHEMICAL & SURFACE INTERACTIONS

Quartz Crystal Microbalance with Dissipation
TALK TO OUR TEAM

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

BIOMOLECULAR INTERACTIONS | PROTEIN AGGREGATION & INTERACTION | SURFACTANT & FORMULATION COMPOSITION ANALYSIS

QUANTITATIVE | REAL-TIME | CHEMICAL & SURFACE INTERACTIONS

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Quartz Crystal Microbalance with Dissipation (QCM-D)

Providing answers about mass and structural changes at the nanoscale level with nanogram precision for a wide variety of samples and measurement conditions.

Quantitative Surface & Interface Contamination

Qualitative analysis such as visual inspection of a surface lacks quantitative data. For example, understanding how cleaning agents are performing, from removal rates to total mass removal, is vital to the development of products from CMP Slurries to surfactant in dish detergent. Quartz crystal microbalance delivers quantitative data on how surface and solutions interact at molecular levels, bringing quantitative data to some outdated qualitative testing procedures.

QSense Pro

Standard Capabilities

  • Up to four measurements can be performed in parallel
  • Minimum liquid sample volume: ~300 μL
  • Temperature range: 15-150 °C +/- 0.02 °C
  • Typical flow rates: 25-300 μL/min
  • Normal mass sensitivity in liquid: 1.8 ng/cm2
  • Normal dissipation sensitivity in liquid: 0.110-6
  • Maximum time resolution (running one sensor and one frequency): 10 ms

Additional Capabilities

Standard flow module:

Standard module for liquid or gaseous samples.

PTFE module:

Replaces the titanium flow path of standard flow module with PTF for flow or stagnant measurements where the reagents or molecules are sensitive to interactions with titanium.

Ideal for research on:

  • Nanoparticle interactions
  • Protein interactions
  • Surfactant and detergent interactions
  • Biomaterial screening
  • Hydrolysis
  • Asphaltene adsorption

Open module:

For low volume samples without flow, volumes down to ~50 μL.

Ideal for research on:

  • Pharmacology
  • Mammalian cells
  • Self-assembly
  • UV curing properties

Humidity module:

To study film interactions such as swelling in contact with different vapors and relative humidity.

Ideal for research on:

  • Film and coating hydration
  • Polymer swelling
  • Food science
  • Protein hydration
  • Paper and print
  • Cellulose

Materials

  • Compatible with aqueous and non-aqueous solutions and aggressive solvents
  • Example compatible solvents:
    • Diluted crude oil
    • Toluene and other aromatic hydrocarbons
    • Hexane and other alkanes
    • Tetramethylammonium hydroxide (TMAH)
    • Ethanol and other alcohols
    • Hydrochloric acid and other acids
    • Sodium hydroxide and other bases
    • Dimethylformamide (DMF)
    • Hexafluoroisopropanol (HFIP)
    • And more! (inquire about your application)

Application Examples

  • Protein interaction with container/packaging
  • Biomolecule interactions with surfaces
  • Flavor and fragrance intensity evaluation
  • Detergency effectiveness and surface cleanliness
  • Cellular interactions in solution and surfaces
  • Quantitative polymer cross-linking
  • Biomolecular binding kinetics
  • Chromatographic detection
  • Viscoelastic modeling

Questions about our QCM-D capabilities?

Contact us for additional information.